The NAT-1 (Neural Activity Tracker) is a highly miniaturised wireless electronic recording system created in an industry-academic collaboration by the Universities of York, Aberdeen, and Cybula Ltd., with specific applications in rodent-based neuroscience.
In preclinical research, rodent electroencephalography (EEG) is often used in acting animals. The difficulty in distinguishing EEG epochs connected with a specific behaviour or trigger, on the other hand, is a substantial impediment to more efficient analysis. This study, presents a novel method for successfully synchronising EEG from superficial sites above the hippocampus and prefrontal cortex with video motion tracking data in a transgenic Alzheimer’s disease (AD) animal model using infrared event stamping. Prior to further investigation, epochs capturing specified behaviours were automatically recognised and retrieved. This was accomplished by the development of a revolutionary ultra-miniature wearable EEG recorder, the NAT-1 device, and its in-situ IR recording module. The device is thoroughly detailed, and its importance to the advancement of novel neuroscience is demonstrated.
Crispin-Bailey, Christopher orcid.org/0000-0003-0613-9698, Austin, James orcid.org/0000-
0001-5762-8614, Moulds, Anthony et al. (2 more authors) (2019) Miniature Untethered
EEG Recorder Improves Advanced Neuroscience Methodologies. IEEE Transactions on
Biomedical Circuits and Systems. pp. 1101-1111. ISSN 1932-4545